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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82774 | Caspase-3 activator 3 | Caspase | |
Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemic activity with IC50 values of 42.89 μM and 33.61 μM, respectively... | |||
T82775 | Caspase-3 activator 2 | Caspase | |
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM, respectively [1]. It facilitates apoptosis, rendering it usef... | |||
T79743 | Caspase-3 activator 1 | Pyroptosis | |
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This cleavage enables Caspase-3 to process gasdermin E (GSDME), whic... | |||
T72316 | Caspase-3/7 activator 3 | ||
Caspase-3/7 Activator 3 is a potent and tumor-selective compound that effectively activates Caspase-3/7, demonstrating significant anti-proliferative activity and a high capacity to induce apoptosis. | |||
T72315 | Caspase-3/7 activator 2 | ||
Caspase-3/7 Activator 2 is a potent compound that selectively activates Caspase-3/7, demonstrating tumor specificity, anti-proliferative properties, and a high capacity for inducing apoptosis. | |||
T8652 | CASP3 Activator 1541 | Caspase | |
CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death. | |||
T1772 | MDK83190 | Apoptosis Activator 2 | Apoptosis , Caspase |
MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation . | |||
T12413 | PETCM | Others | |
PETCM is a caspase-3 activator and acts as an cytochrome c (cyto c)-dependent manner. | |||
T71336 | CASP3 Activator 1541B | ||
CASP3 Activator 1541B is an activator of the proenzyme forms of caspase-3, and is an inducer of cell death. | |||
T38637 | Roy-Bz | ||
Roy-Bz is a potent and selective activator of protein kinase C delta (PKCδ). It effectively inhibits proliferation in colon cancer cells by initiating a mitochondrial apoptotic pathway that relies on PKCδ and involves th... | |||
T25032 | ALC67 | ALC-67,ALC 67 | |
ALC67 has a promising anticancer activity that results in the recent discovery of a series of 3-propionyl thiazolidine-4-carboxylic acid ethyl esters as a family of novel antiproliferative agents. It is an activator of t... | |||
T69323 | Dexamethasone sodium succinate | ||
Dexamethasone sodium succinate is the acetate salt form of dexamethasone, which is a synthetic glucocorticoid; it combines high anti-inflammatory effects with low mineralocorticoid activity. At high doses (e.g. 40 mg), i... |